LEAD OPTIMIZATION

  • GENEPEP offers its expertise in peptide chemistry for transforming your hits in lead compounds

  • Through SAR studies, Genepep designs and synthesizes analogs of your molecule of interest for:

    • Increasing stability, solubility, specificity and efficacy
    • Reduce production cost
    • Create new IP
  • Structure-Activity studies

    Identification of minimal active sequence, Ala scan, Gly-scan, D-scan, design of oriented libraries (analogs), incorporation of unnatural, exotic amino acid, peptide mimics, original cyclization …