New Publication on Protein Synthesis – Ubiquitine

GENEPEP in collaboration with SERVIER published new publication on Ubiquitine studies. During the project GENEPEP was responsible for the chemical synthesis of the Ubiquitine coupled to different peptidic substrates through side chain of the lysine.

M. Bacchi, B. Fould, M. Jullian, A. Kreiter, A. Maurras, O. Nosjean, T. Coursindel, K. Puget, G. Ferry and J. A. Boutin, Screening ubiquitin specific protease activities using chemically synthesized ubiquitin and ubiquitinated peptides, Anal Biochem, 2017, 519, 57-70.

New publication on Protein Synthesis

GENEPEP in collaboration with SERVIER published latest results on Calstabin 2 studies. GENEPEP was responsible for the chemical synthesis of the protein by Native Chemical Ligation (NCL).

M. Bacchi, M. Jullian, S. Sirigu, B. Fould, T. Huet, L. Bruyand, M. Antoine, L. Vuillard, L. Ronga, L. M. Chavas, O. Nosjean, G. Ferry, K. Puget and J. A. Boutin, Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6), Protein Sci, 2016, 25, 2225-2242.